axon
img

Axon is made of 8 plant based, brain-boosting nutrients that help improve mental fluency, memory retention, and cognitive fitness.

$33
Deliver every:
NEURONS THAT FIRE TOGETHER WIRE TOGETHER
The Four Ways Our Brain Adapts
Neurogenesis - The growth and development of new nerve tissue
Weakened Synapses - Connections that aren't used in the brain become weak
New Synapses - New skills and experiences create new neural connections
Strengthened Synapses - Repetition and practice strengthen neural connections
Build a Better Brain
The Pathway to a Better Brain
Set goals
Maintain awareness
Make conscious decisions
Seek rewards and satisfaction from healthy sources
New pathways are formed
New habits are strengthened
Engineered Using Research-Backed Ingredients
Cognition

In this study, 30 participants were given either a Placebo or Lion’s Mane extract daily for 16 weeks. Research has demonstrated that the 750mg of Lion’s Mane group exhibited higher cognitive performance scores when compared to the placebo.

Working Memory

A randomized double-blind study with 62 participants was conducted over a 90 day period. The Bacopa monnieri group showed statistically significant improvement in working memory, visual information processing, and accuracy in complex cognitive tasks when compared to the placebo group. Participants in the study took 300mg of Bacopa monnieri daily.

Strengthen the mind

Designed to improve memory, cognition, and overall brain support. Build a better brain.

img
$33
Deliver every:
Ingredients with Purpose
Lion's Mane Extract (30% Beta-D-Glucans) - 500mg

Lion’s Mane, also known as Hericium erinaceus, is a remarkable mushroom that has been used in Chinese medicine for centuries. This mushroom has shown to promote the development of new nerves and to enhance brain function, even after the user has stopped taking it.

Source

Lion’s Mane Mushroom is native to China, Japan, North America, and Europe.

Benefits

Promotes the growth of Nerve Growth Factor (NGF)

Enhances cognition by reducing inflammation in the brain

Supports overall brain health

How it works

Lion’s Mane helps improve cognition by increasing the amount of Nerve Growth Factors in the brain. Nerve Growth Factors are small proteins that are essential to the development, maintenance, and longevity of neurons. Nerve Growth Factors have also been shown to play a vital role in myelination, which is the development of the protective coating around the axons called the myelin sheath.

Side Effects

There have been very few side effects reported during Lion’s Mane supplementation. The major side effect experienced is a sensation of itchy skin, which may be explained by an increase in Nerve Growth Factors in the body.

Published Studies

https://www.ncbi.nlm.nih.gov/pubmed/18844328
https://www.ncbi.nlm.nih.gov/pubmed/26853959
https://www.ncbi.nlm.nih.gov/pubmed/23510212

Bacopa Monnieri Extract (50% Bacopasides) - 200mg

Standardized to 50% extract

Bacopa monnieri is one of the oldest and most studied nootropic compounds to date. Bacopa has centuries of use in Ayurvedic medicine as a cognition enhancer, stress reliever, and brain protectant. Bacopa monnieri is different from many modern nootropics as it must be taken over a long period of time to achieve maximum results.

Source

Bacopa is found naturally in southern India and is also found in warm wetlands throughout Asia and the southern United States.

Benefits

Enhances memory formation and recall

Significantly improves spatial learning

Protects the brain through its antioxidant properties

How it works

Bacopa monnieri extract contains Bacoside-A, which has been shown to stimulate nerve cells and improve synapse sensitivity to nerve impulses. Bacopa has also been shown to stimulate the hippocampus by increasing the activity of proteins that regulate cellular pathways in the brain. Studies have also shown that Bacopa’s active ingredients support GABA activity, which helps restrict the firing of neurons that are over-excited by stress.

Side Effects

Bacopa is generally recognized as safe at moderate doses between 200mg – 400mg,with minimal side effects. Most side effects are dose-dependent. Common side effects include indigestion, dry mouth, and increased bowel movements, which commonly dissipate over time as the body becomes accustomed to Bacopa.

Published Studies

https://www.ncbi.nlm.nih.gov/pubmed/20228219
https://www.ncbi.nlm.nih.gov/pubmed/20703343
https://www.ncbi.nlm.nih.gov/pubmed/19808086

Citicoline (CDP-Choline) - 200mg

CDP-Choline is naturally found in small amounts in the body and is extracted commercially from purified soy lecithin. CDP-Choline is a potent memory booster and also acts a powerful potentiator of other nootropics. Choline supplementation can be difficult to achieve solely through dietary means, as significant sources such as meat and dairy products are well below concentrations needed for supplementation.

Source

CDP-Choline is found naturally in soy and sunflowers.

Benefits

Memory enhancement
Protection against brain aging
Promotes rapid recovery after physical exercise
Amplifies effects of other nootropics
Significantly improves spatial learning

How it works

CDP-Choline is water soluble and easily crosses the blood-brain barrier, where it is metabolized into essential choline for the brain. Choline is a precursor to the neurotransmitter acetylcholine, which has been shown to be involved in cognitive functions such as memory formation, learning ability, and concentration. CDP-Choline has also been shown to affect the production of HGH (human growth hormone) in the pituitary glands, which stimulates cell growth and repair.

Side Effects

CDP-Choline is safe and well tolerated in healthy adults, but some side effects such as headaches and nausea have been reported by a small percentage of study participants.

Ginkgo Biloba Extract (24% Glycosides) - 120mg

The extract from this ancient Chinese tree species has been used as a cognition enhancing supplement for over 500 years.

Benefits

Ginkgo biloba has been shown to improve circulation, cognition, memory, and protect against oxidative stress.

How it works

The antioxidant properties of ginkgo biloba, particularly that of bilobalide, appear to be active at the level of the mitochondria and thus this plant can act as a mitochondrial protective agent. In vitro, bilobalide appears to promote neuronal proliferation and nerve repair.

Side Effects

Patients with blood circulation disorders or individuals on anticoagulants, such as aspirin, are at risk of experiencing undesirable effects after taking ginkgo. Those taking selective serotonin reuptake inhibitors (SSRI) as antidepressants should not take ginkgo as it inhibits monoamine oxidase, reducing the effectiveness of the medications.

Published Studies

https://www.ncbi.nlm.nih.gov/pubmed/24633934

https://www.ncbi.nlm.nih.gov/pubmed/17457961

https://www.ncbi.nlm.nih.gov/pubmed/9823823

Phosphatidylserine 50% - 100mg

Phosphatidylserine is an essential molecule that plays a key role in cell cycle signaling and is a primary building block for the billions of cells in your brain.

Benefits

Phosphatidylserine has been shown to increase your ability to manage stress effectively and improve overall mood. The FDA has even stated that phosphatidylserine “may reduce the risk of dementia and cognitive dysfunction”.

How it works

Phosphatidylserine is a structural component of a cell’s lipid bilayer (cell membrane) with the serine molecule facing inwards. When included in the structure of the cell membrane, it seems to contribute to and increase cell fluidity and have positive influences on the enzymes Na+/K+ stimulated ATPase (upregulation) and acetylcholinesterase (downregulation), which may lead to its effects on cognition.

Side Effects

Supplementation of up to 600mg phosphatidylserine (soy based) for 12 weeks in elderly persons has been noted to not be associated with any adverse effects.

Published Studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966935/

https://www.ncbi.nlm.nih.gov/pubmed/23495677

https://www.ncbi.nlm.nih.gov/pubmed/18616866

Huperzine A 1% - 10mg

Huperzine A is a naturally sourced nootropic that has been used for centuries in China for its ability to enhance memory and cognition.  Huperzine A is a potent memory enhancer and is particularly effective when trying to study or learn any new material.

Source

Huperzine A is derived from the Chinese club moss Huperzia serrata and is native to temperate regions in China.

Benefits

Promote the growth of new nerve cells.

Acts as a potent neuroprotectant.

Improves memory retention and recall.

How it works

Huperzine A increases levels of acetylcholine in the brain by inhibiting cholinesterase, which is the enzyme that breaks down acetylcholine.  Acetylcholine has been shown to assist in the formation of new memories and high acetylcholine levels increase the magnitude of neurotransmissions to the cortex.  It has also been shown in studies to protect neurons from damage caused by glutamates, peroxides, and beta-amyloid build up.

Side Effects

Huperzine A has been shown to be safe for daily use, however it tends to be cycled in order to avoid tolerance build up.  Because Huperzine A has been shown to slow heart rate and affect blood pressure, individuals with heart disease should consult with their physician before taking it.

Published Studies

https://www.ncbi.nlm.nih.gov/pubmed/23454433

https://www.iupac.org/publications/pac/pdf/2007/pdf/7904×0469.pdf

https://www.ncbi.nlm.nih.gov/pubmed/18348466

Vitamin B1 (Thiamine) - 10mg

Vitamin B1, also known as thiamine, was the first B vitamin discovered by researchers. It is an essential vitamin that the body does not produce, so it must be obtained from food or supplementation.

Sources

Vitamin B1 is found in Brewer’s yeast, legumes, fish, poultry, and green leafy vegetables.

Benefits

Enhances mental clarity and focus

Increases energy levels and reduces fatigue

Helps combat the negative effects of stress

How it works

Vitamin B1 forms a coenzyme called thiamine pyrophosphate (TPP), which assists with the metabolism of sugars and amino acids. The brain’s main fuel source is glucose and glucose cannot be metabolized unless enough Vitamin B1 is present. Vitamin B1 has also been shown to help synthesize glutathione, which provides antioxidant protection for brain cells.

Side Effects

No side effects are experienced while taking the daily recommended intake of Vitamin B1, which is between 1.1mg and 1.4mg for adults.

Published Studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/
https://www.hindawi.com/journals/isrn/2013/650983/

Vitamin B6 (Pyridoxal-5-Phosphate) - 10mg

Vitamin B6, also known as Pyridoxal-5-Phosphate, is an essential vitamin that is involved in more than 100 different enzyme reactions in the body. Vitamin B6 is shown to play a vital role in the biosynthesis of five important neurotransmitters: serotonin, dopamine, epinephrine, norepinephrine, and GABA.

Source

Vitamin B6 is found in significant amounts in bananas, turkey, chickpeas, and potatoes.

Benefits

Optimizes blood circulation in the brain

Helps maintain a healthy balance of neurotransmitters

Enhances overall mental performance

How it works

Vitamin B6 helps metabolize homocysteine, which is a type of blood fat that damage blood vessels inside the brain. By breaking down homocysteine, Vitamin B6 plays an important role in regulating brain circulation and maintaining optimal brain health. Vitamin B6 also supports memory recall and attention span through the production of essential neurotransmitters.

Side Effects

Side effects caused by Vitamin B6 are very rare, especially supplementing with a moderate dose. The Mayo Clinic suggests a daily dose of 20mg of Vitamin B6 for cognitive function support.

Published Studies

https://www.ncbi.nlm.nih.gov/pubmed/14584010
https://www.ncbi.nlm.nih.gov/pubmed/8414222

Vitamin B12 (Methylcobalamin) - 100mcg

Vitamin B12, also known as Methylcobalamin, is an essential vitamin that plays vital roles in overall brain function, nervous system health, and energy production. Since Vitamin B12 is water soluble, the body cannot store it for long periods of time and it has to be replenished daily through dietary means.

Source

Dietary sources of Vitamin B12 are red meat, fish, milk, mushrooms, cheese, and shellfish.

Benefits

Promotes healthy brain aging

Improves neural communication

Supports overall brain health

How it works

Vitamin B12 is involved in the formation of S-adenosylmethionine (SAM), which is a compound needed to maintain the overall genetic health of brain tissue. Vitamin B12 has also been shown to speed up nerve impulses by promoting myelin sheath production. Vitamin B12 also acts as a precursor in the biosynthesis of all major neurotransmitters in your brain, such as acetylcholine, dopamine, GABA, norepinephrine, and serotonin.

Side Effects

Vitamin B12 side effects very rarely occur when consumed orally, even when administering a large dose of B12.

Published Studies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874776/
https://www.ncbi.nlm.nih.gov/pubmed/22221769
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237236/

What could you create with a better brain?